Illumina Launches NGS-Based Proteomics Assay Detecting 9,500 Proteins (illumina.com)

• Illumina Protein Prep detects and quantifies ~9,500 unique human proteins from a single serum or plasma sample using NGS readout.
• The fully automated workflow on the Tecan Fluent 780 produces results in under 2.5 days with 4 hours hands-on time.
• Integrated analysis pipeline includes DRAGEN secondary analysis and Illumina Connected Multiomics for multiomics integration.

"Illumina released a new automated NGS-based proteomics solution called Illumina Protein Prep, using SOMAmer aptamers to detect and quantify ~9,500 unique human proteins from plasma or serum. The workflow runs on the Tecan Fluent 780 automation system and NovaSeq sequencers, delivering results in under 2.5 days with 4 hours hands-on time. Integrated analysis with DRAGEN and Illumina Connected Multiomics provides normalization and quantification. The assay offers femtomolar sensitivity and ~5.5% CV reproducibility, targeting applications in biomarker discovery and population genetics."