Gut viromes in collembolans mediate microbial adaptation to pharmaceutical diversity under warming conditions (microbiomejournal.biomedcentral.com)

• Pharmaceutical diversity reduced gut viral diversity in collembolans, but not in surrounding soil.
• Diurnal warming increased lysogenic phage proportion and AMGs (ACADM, nrdA) that enhance thermal tolerance.
• Diverse pharmaceuticals promoted lytic phages and bacterial degradation via 'kill-the-winner' dynamics.
• Warming amplified bacterial disruption and strengthened bacteria-virus networks, supporting viromes as early stress indicators.

"A study in Folsomia candida shows that pharmaceutical diversity reduces gut viral diversity, while warming increases lysogenic phages and auxiliary metabolic genes (ACADM, nrdA) that improve thermal tolerance. Warming amplifies bacterial disruption and strengthens bacteria-virus networks. Results suggest gut viromes are early indicators of combined pharmaceutical and warming stress, supporting One Health risk assessment."