Recombinant LAB-Vectored Multicomponent Vaccine Against Campylobacter jejuni Promotes Healthier Poultry Gut Microbiome (microbiomejournal.biomedcentral.com)

• Vaccine uses recombinant Lactococcus lactis expressing C. jejuni antigens
• Significantly reduces C. jejuni cecal colonization in broilers
• Modulates gut microbiota towards a healthier composition with increased butyrate producers

"A study published in Microbiome journal presents a recombinant lactic acid bacteria (LAB) vector-based multicomponent vaccine targeting Campylobacter jejuni in poultry. The vaccine aims to reduce C. jejuni colonization and simultaneously promote a healthier microbial balance in the gut. The research demonstrates that the vaccine not only elicits immune responses but also modulates the gut microbiota composition, potentially reducing pathogen load while enhancing beneficial bacteria. This approach could offer a dual benefit for poultry health and food safety by decreasing Campylobacter contamination in poultry products."