Genome-wide association study of 619,372 individuals identifies metabolic trait loci from Estonian and UK Biobank data (nature.com)

• Combined data from Estonian Biobank and UK Biobank for 619,372 individuals.
• Identified common and low-frequency genetic loci associated with circulating metabolic traits.
• Enables putative causal inference linking genetic variants to disease outcomes.

"A GWAS combining Estonian Biobank and UK Biobank data from 619,372 individuals identified numerous common and low-frequency genetic loci associated with circulating metabolic traits. The analysis enables putative causal links between genetic variants and disease outcomes, advancing understanding of metabolic disease mechanisms."