PacBio announces SPRQ-Nx chemistry for Revio and Vega platforms to lower genome cost (pacb.com)

• New SPRQ-Nx chemistry reduces genome cost to under $300
• 5hmC detection for epigenetics on Vega and Revio
• 21 CFR Part 11 compliance for Vega in regulated labs

"PacBio announced new SPRQ-Nx sequencing chemistry for its Revio and Vega platforms, aiming to reduce genome cost to under $300 per genome at scale. The chemistry enables 5hmC detection for epigenetics and adds 21 CFR Part 11 compliance for Vega. Beta testing starts November 2025, with commercial availability in 2026. Cost reduction is approximately 40% compared to current pricing."