Micheliolide alleviates colon cancer cachexia via gut microbiota modulation through Phocaeicola vulgatus enrichment (microbiomejournal.biomedcentral.com)

• Micheliolide enriches Phocaeicola vulgatus in gut microbiota.
• This modulation reduces inflammation and muscle wasting in colon cancer cachexia.
• Study identifies a microbiota-immune axis as therapeutic target.

"A study in Microbiome demonstrates that micheliolide, a natural compound, attenuates colon cancer cachexia in mice by enriching Phocaeicola vulgatus in the gut microbiota, which modulates immune signaling."