Identification of approximately 1,700 new microproteins from non-canonical open reading frames in the human proteome (pubmed.ncbi.nlm.nih.gov)
0xBASE INTEL BRIEF
- 95,520 proteomics experiments analyzed
- ~1,700 new microproteins identified
- New 'peptidein' class defined
"The TransCODE Consortium analyzed 95,520 proteomics experiments and found that about 25% of 7,264 non-canonical open reading frames (ncORFs) produce detectable peptides, leading to the identification of approximately 1,700 new microproteins and so-called peptideins. The findings expand the human proteome and are supported by annotation tools in GENCODE and PeptideAtlas."
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