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Spotlight Jul 22

Featured Spotlight

Metabolite Glues as Purine Sensors and Chemotherapeutic Targets: Implications for Drug Discovery, MS-Based Screening, and Omics Landscape

Analysis Briefing

All briefings

7-DAY ROUNDUP

Metaproteomics standardization advances; microbiome studies link dysbiosis to disease risk.

  1. Community benchmarking reveals low reproducibility and need for standardized protocols in mass spectrometry detection of unannotated human microproteins (nature.com) | just now
  2. Great Barrier Reef Microbial Genomes Database constructed via hybrid Nanopore and Illumina sequencing (nature.com) | 5d ago
  3. Gut microbiota regulates fish muscle texture via collagen synthesis (link.springer.com) | 26d ago
  4. Spatial proteome map of human body and cancers from 2,856 DIA-MS samples (nature.com) | 40d ago
  5. Transcriptomic hallmarks of mammalian ageing and mortality identified through multi-species meta-analysis (nature.com) | 61d ago
  6. Genetic analysis of 249 circulating metabolic traits in 619,372 individuals from Estonian and UK Biobanks (nature.com) | 68d ago
  7. Obesogenic diet and gut microbiome synergistically enhance anti-PD-1 efficacy via Lactobacillus johnsonii and aromatic amino acid metabolites (nature.com) | 19d ago
  8. Immunosuppression linked to loss of airway microbiome stability in severe COVID-19 patients (microbiomejournal.biomedcentral.com) | 4d ago
  9. Standardization and open data practices in metaproteomics: community reporting checklist (microbiomejournal.biomedcentral.com) | 4d ago
  10. Non-protein ubiquitin clipping (NoPro-clipping) method identifies ubiquitinated glycogen and metabolites in cells and tissues (nature.com) | 96d ago
  11. Metatranscriptomics reveals osmoregulatory strategies in pink biofilms on salt-weathered historic buildings in Austria (microbiomejournal.biomedcentral.com) | 27d ago
  12. Genetic Analysis of 249 Circulating Metabolic Traits in 619,372 Individuals Identifies 88,127 Associations (nature.com) | 105d ago
  13. Cesarean section-induced gut dysbiosis increases risk of obesity and insulin resistance in high-fat diet mouse model (microbiomejournal.biomedcentral.com) | 5d ago
  14. Designed keystone metabolites boost shrimp disease resistance by recruiting symbionts via lipoxin A4–AP-1 pathway (static-content.springer.com) | 62d ago
  15. Longitudinal microbial source tracking on China Space Station identifies cargo and cabin contributions (microbiomejournal.biomedcentral.com) | 59d ago
  16. α-Ketoglutarate drives carnitine synthesis to promote histone acetylation and homologous recombination DNA repair in cancer cells (nature.com) | 61d ago
  17. QuantUMS: Machine learning-based quantification method improves accuracy and precision in DIA proteomics (nature.com) | 61d ago
  18. Micheliolide alleviates colon cancer cachexia via gut microbiota modulation through Phocaeicola vulgatus enrichment (microbiomejournal.biomedcentral.com) | 62d ago
  19. Metagenomic analysis reveals gut microbiota compositional and functional shifts in female IBS patients (nature.com) | 26d ago
  20. Metaproteomics Initiative Reviews Five Years of Community-Driven Standardization and Benchmarking (microbiomejournal.biomedcentral.com) | 4d ago
  21. Zero-shot de novo peptide sequencing with open posttranslational modification discovery (nature.com) | 69d ago
  22. Inulin restores cognitive function in mouse model of vascular impairment via gut microbiota-SCFA-GPR41/43-GABAergic pathway (microbiomejournal.biomedcentral.com) | 12d ago
  23. Purine nucleotides act as endogenous molecular glues to regulate purine biosynthesis and thiopurine response (nature.com) | 12d ago
  24. Integrated metatranscriptomics identifies Lachnospiraceae as keystone taxa regulating rumen biohydrogenation and milk ω-6/ω-3 polyunsaturated fatty acids ratio in dairy cows (microbiomejournal.biomedcentral.com) | 105d ago
  25. Reduced winter precipitation decreases microbial growth efficiency and alters soil organic carbon composition in California grassland (microbiomejournal.biomedcentral.com) | 107d ago
  26. Ethical challenges and co-laboration framework for global human microbiome research (link.springer.com) | 111d ago
  27. Gut microbiota-derived tryptophan metabolites inhibit pyroptosis via AhR to protect intestinal barrier (microbiomejournal.biomedcentral.com) | 118d ago
  28. Diatom exudate sulfated α-1,3-mannan structures determine specific bacterial colonization in surface ocean microbiome (microbiomejournal.biomedcentral.com) | 123d ago
  29. BATTER deep learning tool predicts bacterial transcription termination across 42,905 genomes (microbiomejournal.biomedcentral.com) | 21d ago
  30. Perspective article reviews lipidomics advances and future directions across health, nutrition, and environment (nature.com) | 60d ago
  31. Environmental reservoirs and transmission pathways of antimicrobial resistance across the pork production continuum (microbiomejournal.biomedcentral.com) | 6d ago
  32. Rhizobacterial functional assemblies modulate DEHP accumulation in choysum (Brassica parachinensis L.) (microbiomejournal.biomedcentral.com) | 6d ago
  33. IL-17A deficiency enriches Prevotella species and promotes Tregs in HLA-DR3 transgenic mice, reducing EAE severity (microbiomejournal.biomedcentral.com) | 28d ago
  34. Integrative Multi-Omics Analysis of Cecal Microbiome in BXD Mice Reveals Diet, Age, and Genotype Effects on Host Phenotypes (microbiomejournal.biomedcentral.com) | 76d ago
  35. Study quantifies functional recovery limitations of whole metagenome sequencing depth in oral microbiome of Nigerian youths (microbiomejournal.biomedcentral.com) | 32d ago
  36. Curcumin Mitigates Aflatoxin B1-Induced Liver Injury in Sheep Through Rumen Microbiota Modulation (microbiomejournal.biomedcentral.com) | 98d ago
  37. Multi-omics study reveals rumen microbiome-metabolite associations with early lactation performance in dairy cows (microbiomejournal.biomedcentral.com) | 111d ago
  38. Ginsenoside Rg3 enriches SCFA-producing Blautia spp. to protect against enteric viral infection via GPR43-cGAS-STING-IFN-I axis in macrophages (nature.com) | 990d ago
  39. Metagenomic analysis of wild boar faecal microbiome reveals novel species and carbohydrate degraders distinguishing wild from domestic pigs (microbiomejournal.biomedcentral.com) | 116d ago
  40. Stochastic assembly influences functional potential, redundancy, and trait patterns in bacterial communities (microbiomejournal.biomedcentral.com) | 48d ago
  41. Arthrobacter nicotine catabolism gene cluster acquired via horizontal transfer enhances fitness in tobacco root microbiota (microbiomejournal.biomedcentral.com) | 12d ago
  42. Commensal gut bacteria produce acetylcholine from dietary choline, enhancing mucosal IgA responses and infection resistance (nature.com) | 54d ago
  43. Mitochondrial L-2-Hydroxyglutarate Identified as Physiological Signalling Metabolite (nature.com) | 62d ago
  44. MdUGT88F1 enhances apple resistance to Fusarium proliferatum via root exudate-mediated assembly of disease-suppressive rhizosphere microbiota (static-content.springer.com) | 62d ago
  45. Subcellular chemical mapping using correlated cryogenic electron and mass spectrometry imaging (nature.com) | 63d ago
  46. Metabolon's UPLC-MS/MS platform used in 2,3-butanediol isomer study on weight gain and glucose in mice (frontiersin.org) | 63d ago
  47. Identification of approximately 1,700 new microproteins from non-canonical open reading frames in the human proteome (pubmed.ncbi.nlm.nih.gov) | 64d ago
  48. Mitochondrial l-2-hydroxyglutarate identified as physiological signalling metabolite controlling postnatal growth and renal function (nature.com) | 68d ago
  49. Limosilactobacillus strains improve feed efficiency in broiler chickens through ornithine-mediated gut microbiota modulation and Nrf2 signaling activation (microbiomejournal.biomedcentral.com) | 17d ago
  50. Asparagopsis taxiformis supplementation reduces methane yield by 54% in dairy cows via vitamin B12-dependent pathway modulation and rumen microbiome restructuring (microbiomejournal.biomedcentral.com) | 45d ago
Showing page 1 of 5 (228 total results)
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