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Spotlight Jun 09

Featured Spotlight

Microprotein Reproducibility Crisis and Path to Clinical Translation: Integration of Benchmarking, Immunopeptidomics, and Regulatory Hurdles

Analysis Briefing

All briefings

7-DAY ROUNDUP

Microbiome breakthroughs: gut metabolites shape immunity and muscle health, while new tools enable decentralized proteomics and viral discovery.

  1. Gut microbiota regulates fish muscle texture via collagen synthesis (link.springer.com) | just now
  2. Metagenomic analysis reveals gut microbiota compositional and functional shifts in female IBS patients (nature.com) | just now
  3. Western vs. agrarian diet effects on gut microbiome and immune dysfunction in HIV patients in Zimbabwe (microbiomejournal.biomedcentral.com) | just now
  4. Community benchmarking reveals low reproducibility and need for standardized protocols in mass spectrometry detection of unannotated human microproteins (nature.com) | just now
  5. Precisely designed keystone metabolites boost shrimp disease resistance by recruiting symbionts via the lipoxin A4–AP-1 pathway (microbiomejournal.biomedcentral.com) | just now
  6. Stochastic assembly influences functional potential, redundancy, and trait patterns in bacterial communities (microbiomejournal.biomedcentral.com) | 6h ago
  7. Transcriptomic hallmarks of mammalian ageing and mortality identified through multi-species meta-analysis (nature.com) | 13d ago
  8. Genetic analysis of 249 circulating metabolic traits in 619,372 individuals from Estonian and UK Biobanks (nature.com) | 20d ago
  9. Designed keystone metabolites boost shrimp disease resistance by recruiting symbionts via lipoxin A4–AP-1 pathway (static-content.springer.com) | 14d ago
  10. Longitudinal microbial source tracking on China Space Station identifies cargo and cabin contributions (microbiomejournal.biomedcentral.com) | 11d ago
  11. α-Ketoglutarate drives carnitine synthesis to promote histone acetylation and homologous recombination DNA repair in cancer cells (nature.com) | 13d ago
  12. QuantUMS: Machine learning-based quantification method improves accuracy and precision in DIA proteomics (nature.com) | 13d ago
  13. Non-protein ubiquitin clipping (NoPro-clipping) method identifies ubiquitinated glycogen and metabolites in cells and tissues (nature.com) | 48d ago
  14. Micheliolide alleviates colon cancer cachexia via gut microbiota modulation through Phocaeicola vulgatus enrichment (microbiomejournal.biomedcentral.com) | 14d ago
  15. Genetic Analysis of 249 Circulating Metabolic Traits in 619,372 Individuals Identifies 88,127 Associations (nature.com) | 57d ago
  16. Zero-shot de novo peptide sequencing with open posttranslational modification discovery (nature.com) | 21d ago
  17. Seed Microbiome: Composition, Functions, and Future Directions in Plant Health and Sustainable Agriculture (link.springer.com) | just now
  18. Ethical framework for global human microbiome research advocates co-laboration to address Western bias (link.springer.com) | just now
  19. Perspective article reviews lipidomics advances and future directions across health, nutrition, and environment (nature.com) | 12d ago
  20. Commensal gut bacteria produce acetylcholine from dietary choline, enhancing mucosal IgA responses and infection resistance (nature.com) | 6d ago
  21. Archaeal Viral Genome Database (AVGD) reveals genomic diversity and host interactions across eight habitats (microbiomejournal.biomedcentral.com) | 1d ago
  22. Integrated metatranscriptomics identifies Lachnospiraceae as keystone taxa regulating rumen biohydrogenation and milk ω-6/ω-3 polyunsaturated fatty acids ratio in dairy cows (microbiomejournal.biomedcentral.com) | 57d ago
  23. Reduced winter precipitation decreases microbial growth efficiency and alters soil organic carbon composition in California grassland (microbiomejournal.biomedcentral.com) | 59d ago
  24. Ethical challenges and co-laboration framework for global human microbiome research (link.springer.com) | 63d ago
  25. Integrative Multi-Omics Analysis of Cecal Microbiome in BXD Mice Reveals Diet, Age, and Genotype Effects on Host Phenotypes (microbiomejournal.biomedcentral.com) | 28d ago
  26. Gut microbiota-derived tryptophan metabolites inhibit pyroptosis via AhR to protect intestinal barrier (microbiomejournal.biomedcentral.com) | 70d ago
  27. Diatom exudate sulfated α-1,3-mannan structures determine specific bacterial colonization in surface ocean microbiome (microbiomejournal.biomedcentral.com) | 75d ago
  28. Mitochondrial L-2-Hydroxyglutarate Identified as Physiological Signalling Metabolite (nature.com) | 14d ago
  29. MdUGT88F1 enhances apple resistance to Fusarium proliferatum via root exudate-mediated assembly of disease-suppressive rhizosphere microbiota (static-content.springer.com) | 14d ago
  30. Subcellular chemical mapping using correlated cryogenic electron and mass spectrometry imaging (nature.com) | 15d ago
  31. Metabolon's UPLC-MS/MS platform used in 2,3-butanediol isomer study on weight gain and glucose in mice (frontiersin.org) | 15d ago
  32. Identification of approximately 1,700 new microproteins from non-canonical open reading frames in the human proteome (pubmed.ncbi.nlm.nih.gov) | 16d ago
  33. Adaptive immune aging alters gut microbiome and reduces systemic vitamin B6 in mouse model (microbiomejournal.biomedcentral.com) | 4d ago
  34. Mitochondrial l-2-hydroxyglutarate identified as physiological signalling metabolite controlling postnatal growth and renal function (nature.com) | 20d ago
  35. Curcumin Mitigates Aflatoxin B1-Induced Liver Injury in Sheep Through Rumen Microbiota Modulation (microbiomejournal.biomedcentral.com) | 50d ago
  36. Multi-omics study reveals rumen microbiome-metabolite associations with early lactation performance in dairy cows (microbiomejournal.biomedcentral.com) | 63d ago
  37. Mass spectrometry method detects ubiquitin on non-protein biomolecules, including glycogen in mouse liver (nature.com) | 6d ago
  38. Metagenomic analysis of wild boar faecal microbiome reveals novel species and carbohydrate degraders distinguishing wild from domestic pigs (microbiomejournal.biomedcentral.com) | 68d ago
  39. Bruker launches timsMRMS, upgrades timsUltra AIP and timsOmni, introduces hybrid metabolomics workflow at ASMS 2026 (bruker.com) | 8d ago
  40. Expanding the human proteome with microproteins and peptideins (nature.com) | 34d ago
  41. Polyethylene microplastics induce liver inflammation in calves via rumen microbiota-gut-liver axis (microbiomejournal.biomedcentral.com) | 35d ago
  42. Study validates mRNA-seq for simultaneous host transcriptome and microbiome profiling in vulvar samples (ncbi.nlm.nih.gov) | 40d ago
  43. Commensal E. coli stabilizes HIF in intestinal epithelium via aerobic respiration in vitro and in vivo (microbiomejournal.biomedcentral.com) | 10d ago
  44. Ginsenoside Rg3 enriches SCFA-producing Blautia spp. to protect against enteric viral infection via GPR43-cGAS-STING-IFN-I axis in macrophages (nature.com) | 942d ago
  45. Deterministic assembly of rhizosphere bacterial community suppresses Verticillium wilt via microbial homeostasis in Astragalus plants, China (microbiomejournal.biomedcentral.com) | 11d ago
  46. Biosynthesized selenium nanoparticles increase soybean resistance to root rot via multiomics-defined dual mechanism in China (microbiomejournal.biomedcentral.com) | 11d ago
  47. Chinese household dust microbiome study quantifies pathogen abundance, virulence factors, and extracellular vesicle contributions (microbiomejournal.biomedcentral.com) | 50d ago
  48. Metabolome-driven rhizosphere microbiome assembly determines health of Angelica sinensis against root rot (microbiomejournal.biomedcentral.com) | 50d ago
  49. Bacillus megaterium KCTC 3007 promotes antitumor immunity in endometrial cancer via TMAO and type I interferon: a multi-omics study on South Korean patients (microbiomejournal.biomedcentral.com) | 50d ago
  50. Genetic analysis of 619,372 individuals identifies over 88,000 metabolic trait associations from Estonian and UK Biobanks (nature.com) | 13d ago
Showing page 1 of 4 (181 total results)
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