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Spotlight Jul 22

Featured Spotlight

Metabolite Glues as Purine Sensors and Chemotherapeutic Targets: Implications for Drug Discovery, MS-Based Screening, and Omics Landscape

  1. Micheliolide reduces colon cancer cachexia through gut microbiota modulation and Phocaeicola vulgatus enrichment (microbiomejournal.biomedcentral.com) | 83d ago
  2. Metagenomics and culturomics reveal dual role of gut microbiome in immune checkpoint inhibitor therapy (microbiomejournal.biomedcentral.com) | 84d ago
  3. Convergent evolution of intestinal lineages in the phylum Methanobacteriota (microbiomejournal.biomedcentral.com) | 86d ago
  4. Streptomyces malaysiensis WHL7 controls banana Fusarium wilt via glycerol-3-phosphate-induced microbiome remodeling (microbiomejournal.biomedcentral.com) | 86d ago
  5. Capsaicin-induced gut microbiota produce 5-aminolevulinic acid to lower blood glucose in mice (microbiomejournal.biomedcentral.com) | 87d ago
  6. Gut microbial metabolite phenylacetylglycine disrupts spermatogenesis in Ggt1-deficient mice via β2AR-STAT3-STAT5B pathway (microbiomejournal.biomedcentral.com) | 97d ago
  7. Genome-resolved multi-omics reveals alternative nitrogen assimilation pathways in rumen microbiota (microbiomejournal.biomedcentral.com) | 103d ago
  8. Multi-omics study reveals microbial decomposer network during brine shrimp carcass decomposition in a Chinese hypersaline lake (microbiomejournal.biomedcentral.com) | 118d ago
  9. Gut viromes in collembolans mediate microbial adaptation to pharmaceutical diversity under warming conditions (microbiomejournal.biomedcentral.com) | 11d ago
  10. Gut microbiota and circulating metabolite associations with inflammation in children: a cohort study using Metabolon untargeted metabolomics and 16S sequencing (bmjopengastro.bmj.com) | 697d ago
  11. Study compares western vs agrarian diet effects on gut microbiome and immune function in HIV+ Zimbabweans (static-content.springer.com) | 177d ago
  12. Quanterix reports insurance coverage and clinical data for multiplex Alzheimer's blood test (bioanalysis-zone.com) | 7d ago
  13. Single-section integration of MALDI-MSI and Xenium spatial transcriptomics at single-cell resolution (nature.com) | 241d ago
  14. Longitudinal study links salivary microbiome changes to chemoradiotherapy response in oral cancer patients (microbiomejournal.biomedcentral.com) | 970d ago
  15. Salivary microbiome changes distinguish response to chemoradiotherapy in patients with oral cancer (link.springer.com) | 1122d ago
  16. Ethical framework for global human microbiome research advocates co-laboration to address Western bias (link.springer.com) | 26d ago
  17. Seed Microbiome: Composition, Functions, and Future Directions in Plant Health and Sustainable Agriculture (link.springer.com) | 26d ago
  18. Giotto Suite: a multiscale and technology-agnostic spatial multiomics analysis ecosystem (nature.com) | 299d ago
  19. International consortium discovers 1,785 microproteins from non-canonical open reading frames, proposes 'peptidein' concept (mdc-berlin.de) | 81d ago
  20. Stable noncanonical peptides identified across five eukaryotes using ribosome profiling and ORF feature analysis (nature.com) | 877d ago
  21. Puerarin modulates gut-liver-ovarian axis to improve reproductive performance in aged breeder hens (microbiomejournal.biomedcentral.com) | 97d ago
  22. Loss of Salivary Agglutinin (DMBT1) Alters Salivary Microbiome and Accelerates Oral Squamous Cell Carcinoma Development in Mice (microbiomejournal.biomedcentral.com) | 108d ago
  23. Ethical concerns in human microbiome research: bias, inclusion, and co-laboration framework (microbiomejournal.biomedcentral.com) | 111d ago
  24. Black soldier fly larvae use compartmentalized immune regulation to recruit lignocellulose-degrading gut symbionts (microbiomejournal.biomedcentral.com) | 48d ago
  25. Cystic fibrosis respiratory microbiota remodelling over three years of elexacaftor–tezacaftor–ivacaftor therapy in a multi-centre cohort (microbiomejournal.biomedcentral.com) | 58d ago
  26. Study identifies Pantoea ananatis as a regulator of adaptive thermogenesis and lipid metabolism in high-altitude macaques (microbiomejournal.biomedcentral.com) | 60d ago
  27. Multi-omics reveals effects of several rumen bacteria on reproductive performance of sheep (microbiomejournal.biomedcentral.com) | 62d ago
  28. Recombinant LAB-Vectored Multicomponent Vaccine Against Campylobacter jejuni Promotes Healthier Poultry Gut Microbiome (microbiomejournal.biomedcentral.com) | 62d ago
  29. Multi-omics study shows Enterococcus faecalis JM263 reduces liver injury in goats on high-concentrate diet via gut-liver axis (microbiomejournal.biomedcentral.com) | 66d ago
  30. Genome-wide association study of 619,372 individuals identifies metabolic trait loci from Estonian and UK Biobank data (nature.com) | 68d ago
  31. Mass spectrometry benchmarking study assesses reliability of reported human microprotein detections (nature.com) | 187d ago
  32. Merck agrees to acquire Bio-Techne for $11.3 billion to expand life sciences and multiomics capabilities (bioanalysis-zone.com) | 27d ago
  33. Geographic genetic divergence and ecological viral communities drive virome diversity in rice pest Chilo suppressalis (microbiomejournal.biomedcentral.com) | 81d ago
  34. RNA-seq reveals active microbiome functional roles across coral Porites lutea compartments (microbiomejournal.biomedcentral.com) | 86d ago
  35. Gastrointestinal microbial nitrogen metabolism shapes nitrogen use efficiency in goats fed soybean meal vs. corn gluten meal (microbiomejournal.biomedcentral.com) | 98d ago
  36. Spermine identified as endogenous iron chelator that inhibits ferroptosis in hepatocellular carcinoma (nature.com) | 54d ago
  37. Exact Sciences launches Cancerguard multi-cancer blood test with Quest Diagnostics partnership (fiercebiotech.com) | 62d ago
  38. Gut microbiome composition and immune dysfunction in HIV patients in Zimbabwe linked to western vs agrarian diet (microbiomejournal.biomedcentral.com) | 76d ago
  39. MdUGT88F1 modulates apple rhizosphere microbiota to control replant disease in China (microbiomejournal.biomedcentral.com) | 83d ago
  40. NeoGenomics Makes Oncology Test Ordering Available Through Epic Aura EHR Integration (ir.neogenomics.com) | 95d ago
  41. Handheld breath test accurately detects fat burning by measuring acetone in a single exhalation (nature.com) | 4d ago
  42. Commentary calls for ethical, locally led microbiome research to address global inequities (microbiomejournal.biomedcentral.com) | 111d ago
  43. Functional landscape of non-canonical open reading frames in coordinating cell fate (pubmed.ncbi.nlm.nih.gov) | 130d ago
  44. Metagenomic analysis of museum nudibranch specimens reveals uncultured symbionts with biosynthetic gene clusters (microbiomejournal.biomedcentral.com) | 27d ago
  45. NeoGenomics Launches RaDaR ST, Expanding MRD Testing Across Multiple Solid Tumors (businesswire.com) | 152d ago
  46. Bruker Launches timsMRMS, Advances 4D Proteomics and Hybrid Metabolomics at ASMS 2026 (bruker.com) | 56d ago
  47. Uterine microbiome shifts from stochastic to deterministic assembly in aged laying hens, with Rhodococcus ruber spermidine production rescuing oxidative phosphorylation impairment (microbiomejournal.biomedcentral.com) | 59d ago
  48. Mass Spec Roundup: Transformer-Based Peptide Sequencing, PM2.5 Molecular Profiling, Sediment Imaging, Glycan Aging Clock, and Dog Breath Analysis (theanalyticalscientist.com) | 61d ago
  49. Large-scale proteomics identifies 25% of non-canonical ORFs produce peptides; peptidein classification introduced (nature.com) | 64d ago
  50. Recombinant Lactococcus lactis multicomponent mucosal vaccine reduces Campylobacter jejuni colonization and shifts poultry gut microbiota (microbiomejournal.biomedcentral.com) | 81d ago
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