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Spotlight Jun 09

Featured Spotlight

Microprotein Reproducibility Crisis and Path to Clinical Translation: Integration of Benchmarking, Immunopeptidomics, and Regulatory Hurdles

  1. Community benchmarking reveals low reproducibility and need for standardized protocols in mass spectrometry detection of unannotated human microproteins (nature.com) | just now
  2. Precisely designed keystone metabolites boost shrimp disease resistance by recruiting symbionts via the lipoxin A4–AP-1 pathway (microbiomejournal.biomedcentral.com) | just now
  3. Genetic analysis of 249 circulating metabolic traits in 619,372 individuals from Estonian and UK Biobanks (nature.com) | 20d ago
  4. QuantUMS: Machine learning-based quantification method improves accuracy and precision in DIA proteomics (nature.com) | 13d ago
  5. Designed keystone metabolites boost shrimp disease resistance by recruiting symbionts via lipoxin A4–AP-1 pathway (static-content.springer.com) | 14d ago
  6. Genetic Analysis of 249 Circulating Metabolic Traits in 619,372 Individuals Identifies 88,127 Associations (nature.com) | 57d ago
  7. Non-protein ubiquitin clipping (NoPro-clipping) method identifies ubiquitinated glycogen and metabolites in cells and tissues (nature.com) | 48d ago
  8. Perspective article reviews lipidomics advances and future directions across health, nutrition, and environment (nature.com) | 12d ago
  9. α-Ketoglutarate drives carnitine synthesis to promote histone acetylation and homologous recombination DNA repair in cancer cells (nature.com) | 13d ago
  10. Zero-shot de novo peptide sequencing with open posttranslational modification discovery (nature.com) | 21d ago
  11. Mitochondrial L-2-Hydroxyglutarate Identified as Physiological Signalling Metabolite (nature.com) | 14d ago
  12. Metabolon's UPLC-MS/MS platform used in 2,3-butanediol isomer study on weight gain and glucose in mice (frontiersin.org) | 15d ago
  13. Subcellular chemical mapping using correlated cryogenic electron and mass spectrometry imaging (nature.com) | 15d ago
  14. Mitochondrial l-2-hydroxyglutarate identified as physiological signalling metabolite controlling postnatal growth and renal function (nature.com) | 20d ago
  15. Multi-omics study reveals rumen microbiome-metabolite associations with early lactation performance in dairy cows (microbiomejournal.biomedcentral.com) | 63d ago
  16. Mass spectrometry method detects ubiquitin on non-protein biomolecules, including glycogen in mouse liver (nature.com) | 6d ago
  17. Lipidomics Perspective Article Outlines Roadmap for Basic Research to Societal Applications (nature.com) | 19d ago
  18. Bacillus megaterium KCTC 3007 promotes antitumor immunity in endometrial cancer via TMAO and type I interferon: a multi-omics study on South Korean patients (microbiomejournal.biomedcentral.com) | 50d ago
  19. Streptomyces-induced Glycerol-3-Phosphate Enriches Beneficial Microbiota to Suppress Banana Fusarium Wilt (static-content.springer.com) | 14d ago
  20. Coral color morphs show distinct proteomic and microbiome profiles in Red Sea study (microbiomejournal.biomedcentral.com) | 68d ago
  21. Multi-omics analysis links rumen bacterial communities to sheep fertility across reproductive stages (microbiomejournal.biomedcentral.com) | 27d ago
  22. Human Microprotein Atlas platform annotates over 600,000 microproteins (nature.com) | 28d ago
  23. Gut microbial metabolite phenylacetylglycine disrupts spermatogenesis in Ggt1-deficient mice via β2AR-STAT3-STAT5B pathway (microbiomejournal.biomedcentral.com) | 49d ago
  24. Gut microbiota and circulating metabolite associations with inflammation in children: a cohort study using Metabolon untargeted metabolomics and 16S sequencing (bmjopengastro.bmj.com) | 649d ago
  25. Single-section integration of MALDI-MSI and Xenium spatial transcriptomics at single-cell resolution (nature.com) | 193d ago
  26. Study identifies Pantoea ananatis as a regulator of adaptive thermogenesis and lipid metabolism in high-altitude macaques (microbiomejournal.biomedcentral.com) | 12d ago
  27. Mass spectrometry benchmarking study assesses reliability of reported human microprotein detections (nature.com) | 139d ago
  28. Mass Spec Roundup: Transformer-Based Peptide Sequencing, PM2.5 Molecular Profiling, Sediment Imaging, Glycan Aging Clock, and Dog Breath Analysis (theanalyticalscientist.com) | 13d ago
  29. Large-scale proteomics identifies 25% of non-canonical ORFs produce peptides; peptidein classification introduced (nature.com) | 16d ago
  30. Metabolomic data of rumen fluid from sheep under aflatoxin B1 and curcumin treatment (ngdc.cncb.ac.cn) | 381d ago
  31. LC-HRMS non-target analysis reveals contrasting organic aerosol composition between urban and agricultural Po Valley sites (acp.copernicus.org) | 21d ago
  32. Metabolon Launches Verus Metabolomics Profiling Kit for In-Lab Use (metabolon.com) | 39d ago
  33. Agilent introduces 8890B and 8860B gas chromatographs with integrated GC Assist intelligence (bioanalysis-zone.com) | 11d ago
  34. King's College London's Melanie Bailey discusses biomarker discovery, non-invasive sampling, and LC-MS/MS in translational research (bioanalysis-zone.com) | 19d ago
  35. Alamar Biosciences launches NULISA Dried Blood Spot Extraction Kit for home-collected fingerstick samples (bioanalysis-zone.com) | 7d ago
  36. Bruker Stock Forecast Highlights Biocrates Acquisition Impact on Life Sciences Tools Market (simplywall.st) | 16d ago
  37. Metabolomic Dataset of Sheep Rumen Fluid Under Aflatoxin B1 Interference from Jilin University (ngdc.cncb.ac.cn) | 378d ago
  38. New Discoveries of Non-Canonical Open Reading Frames Expand the Human Proteome (youtube.com) | 14d ago
  39. Data Release: Autophagy and Dysbiosis Study on Drosophila Gut Metagenome (ngdc.cncb.ac.cn) | 351d ago
Showing page 1 of 1 (40 total results)
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